Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604545 | 1.00 | CTBP2 (0.48) | CTBP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL3966062 | 0.86 | CTBP2 (0.56) | CTBP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL27399090 | 0.81 | CTBP2 (0.48) | CTBP2ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL7095690 | 0.81 | ALDH1A1 (0.46) | CTBP2ALDH1A1MAPTGAALMNA | |
| SCHEMBL2640208 | 0.80 | CTBP2 (0.50) | CTBP2ALDH1A1MAPTGAALMNA | |
| Biphenyl SCHEMBL27544513 | 0.79 | MAPT (0.48) | ALDH1A1MAPTGAALMNACES2 | |
| SCHEMBL27552001 | 0.79 | HTT (0.41) | ALDH1A1MAPTGAAHTTSMN1; SMN2 | |
| SCHEMBL7608511 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KMT2ASMN1; SMN2TP53KDM4E | |
| SCHEMBL7608510 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KMT2ASMN1; SMN2TP53KDM4E | |
| Catechol SCHEMBL10950947 | 0.78 | GAA (0.49) | CTBP2ALDH1A1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174033-B2 | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2019-01-08 | — | — | US | disclosed |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2013-02-21 | — | — | US | disclosed |
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |
| WO-2007072089-A1 | MGLUR5 ANTAGONISTIC CARBAMOYL-OXIME DERIVATIVES | RICHTER GEDEON VEGYÉSZETU GYÁR RT. (HU) | 2007-06-28 | — | — | WO | disclosed |
| EP-0542617-B1 | Method for the preparation of an oximesilane compound | SHINETSU CHEMICAL CO (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5241095-A | METHOD FOR THE PREPARATION OF AN OXIMESILANE COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0542617-A1 | Method for the preparation of an oximesilane compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5171872-A | Method for the preparation of an oximesilane without coloration | SHIN-ETSU CHEMICAL COMPANY, LIMITED (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0417167-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | AlliedSignal Inc. (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989011473-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | ALLIED-SIGNAL INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| EP-0158159-B1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS AND THE CONVERSION THEREOF INTO THE CORRESPONDING HYDROXYLAMINE O-SUBSTITUTED | AlliedSignal Inc. (US) | 1988-10-05 | — | — | EP | disclosed |
| EP-0082324-B1 | PRODUCING OXIMINOSILANES, OXIMINOGERMANES AND OXIMINOSTANNANES | ALLIED CORPORATION (US) | 1987-01-14 | — | — | EP | disclosed |
| EP-0098369-B1 | PRODUCING ALKOXYSILANES AND ALKOXY-OXIMINOSILANES | ALLIED CORPORATION (US) | 1986-07-30 | — | — | EP | disclosed |
| EP-0158159-A1 | Process for the synthesis of o-substituted oxime compounds and the conversion thereof into the corresponding hydroxylamine o-substituted | AlliedSignal Inc. (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0098369-A2 | Producing alkoxysilanes and alkoxy-oximinosilanes | ALLIED CORPORATION (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4400527-A | Producing oximinosilanes, oximinogermanes and oximinostannanes | ALLIED CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0082324-A2 | Producing oximinosilanes, oximinogermanes and oximinostannanes | ALLIED CORPORATION (US) | 1983-06-29 | — | — | EP | disclosed |
| US-4380660-A | SILYLATION, DEHYDROHALOGENATION | ALLIED CORPORATION (US) | 1983-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174033-B2 | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | ADORA2A, ADORA3, ADORA1 | CTBP2 4568/4885ALDH1A1 1674/4885MAPT 117/4885 |
| US-20130045942-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES AND N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | ADORA2A, ADORA3, ADORA1 | CTBP2 4568/4885ALDH1A1 1674/4885MAPT 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.