Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661799 | 0.75 | USP2 (0.44) | ESR1USP2HPGDHSD17B10KMT2A | |
| SCHEMBL28257070 | 0.74 | ESR1 (0.63) | ESR1USP2HPGDHSD17B10KMT2A | |
| SCHEMBL15220259 | 0.70 | LMNA (0.43) | HPGDHSD17B10KMT2AALDH1A1KDM4E | |
| SCHEMBL6855933 | 0.70 | L3MBTL1 (0.41) | ESR1USP2HPGDHSD17B10KMT2A | |
| SCHEMBL9822673 | 0.69 | LMNA (0.42) | ESR1HSD17B10KMT2AALDH1A1MEN1 | |
| SCHEMBL27518822 | 0.66 | HPGD (0.42) | USP2HPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL21016338 | 0.66 | NPC1 (0.39) | USP2HPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9678526 | 0.66 | ALDH1A1 (0.41) | USP2HPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL7288060 | 0.65 | MAPK1 (0.58) | USP2HPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL7057526 | 0.65 | PTGER1 (0.44) | ESR1KMT2AALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263899-A2 | INKS | Avecia Limited (GB) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062859-A2 | INKS | AVECIA LIMITED (GB) | 2001-08-30 | — | — | WO | disclosed |