Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 4/20 | 0.32 |
| ▸ | GABRD | O14764 | 4/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.32 |
| ▸ | GABRE | P78334 | 4/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678306 | 0.87 | CUL4A (0.39) | CUL4AALOX5ALDH1A1GABRPGABRD | |
| SCHEMBL7608682 | 0.87 | KDM4E (0.34) | CUL4AALDH1A1KDM4EICAM1SELE | |
| SCHEMBL9678280 | 0.81 | CUL4A (0.40) | CUL4AALOX5ALDH1A1KDM4ETYMS | |
| SCHEMBL9233277 | 0.80 | DPP4 (0.40) | CUL4AALDH1A1KDM4EDPP4POLB | |
| SCHEMBL8649523 | 0.80 | HCAR2 (0.34) | ALDH1A1ICAM1SELEVCAM1POLB | |
| SCHEMBL9678275 | 0.78 | CUL4A (0.41) | CUL4AALOX5ALDH1A1KDM4EPOLB | |
| SCHEMBL8566455 | 0.78 | SMN1; SMN2 (0.36) | CUL4AALOX5ALDH1A1KDM4ECA2 | |
| SCHEMBL8563058 | 0.75 | TDP1 (0.43) | CUL4A | |
| SCHEMBL8558386 | 0.74 | MAPT (0.46) | ALDH1A1KDM4EPOLB | |
| SCHEMBL11784015 | 0.71 | HSD17B10 (0.35) | CUL4AALDH1A1KDM4EDRD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820987-B1 | Process for the preparation of pyridine-2,3-dicarboxylic acid esters | LONZA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0820987-A1 | Process for the preparation of pyridine-2,3-dicarboxylic acid esters | LONZA AG (CH) | 1998-01-28 | — | — | EP | disclosed |