Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678280 | 0.84 | CUL4A (0.40) | CUL4ALMNAALDH1A1ALOX5MEN1 | |
| SCHEMBL9678306 | 0.82 | CUL4A (0.39) | CUL4AALDH1A1ALOX5KMT2ADPP4 | |
| SCHEMBL9678275 | 0.82 | CUL4A (0.41) | SMN1; SMN2CUL4ACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL9233277 | 0.81 | DPP4 (0.40) | SMN1; SMN2CUL4ACYP3A4ALDH1A1KDM4E | |
| SCHEMBL8563058 | 0.78 | TDP1 (0.43) | SMN1; SMN2CUL4ALMNACYP1A2MEN1 | |
| SCHEMBL7608571 | 0.78 | CUL4A (0.36) | CUL4AALDH1A1ALOX5KDM4EDPP4 | |
| SCHEMBL8558386 | 0.77 | MAPT (0.46) | SMN1; SMN2LMNACYP1A2ALDH1A1MEN1 | |
| SCHEMBL8561228 | 0.76 | KDM4E (0.39) | SMN1; SMN2CUL4ALMNAALDH1A1ALOX5 | |
| SCHEMBL8565917 | 0.76 | KDM4E (0.39) | SMN1; SMN2CUL4ALMNAALDH1A1ALOX5 | |
| SCHEMBL5711950 | 0.74 | LMNA (0.47) | SMN1; SMN2CUL4ALMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663399-B1 | Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants | BASF AG (DE) | 1998-06-10 | — | — | EP | disclosed |
| EP-0663399-A1 | Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants | BASF AKTIENGESELLSCHAFT (DE) | 1995-07-19 | — | — | EP | disclosed |