Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.33 |
| ▸ | SELE | P16581 | 2/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608571 | 0.87 | CUL4A (0.36) | KDM4EICAM1SELECUL4AALDH1A1 | |
| SCHEMBL8649523 | 0.83 | HCAR2 (0.34) | ICAM1SELEALDH1A1GAAVCAM1 | |
| SCHEMBL7608027 | 0.79 | KDM4E (0.39) | KDM4EHPGDHSD17B10CUL4AALDH1A1 | |
| SCHEMBL11784015 | 0.75 | HSD17B10 (0.35) | KDM4EHPGDHSD17B10CUL4AALDH1A1 | |
| SCHEMBL8785398 | 0.73 | CSF1R (0.38) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9678306 | 0.73 | CUL4A (0.39) | CUL4AALDH1A1 | |
| SCHEMBL8786349 | 0.71 | SCN9A (0.37) | SMN1; SMN2GAAMAPTHTT | |
| SCHEMBL8090536 | 0.68 | PTGS2 (0.47) | KDM4EHPGDHSD17B10HTT | |
| SCHEMBL7808610 | 0.68 | ALOX15 (0.44) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL8099009 | 0.67 | ACACB (0.41) | HPGDCUL4AALDH1A1SMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820987-B1 | Process for the preparation of pyridine-2,3-dicarboxylic acid esters | LONZA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0820987-A1 | Process for the preparation of pyridine-2,3-dicarboxylic acid esters | LONZA AG (CH) | 1998-01-28 | — | — | EP | disclosed |