Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 13/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | CCR2 | P41597 | 1/20 | 0.60 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675122 | 1.00 | CXCR4 (0.60) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL674927 | 0.80 | CXCR4 (0.65) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL7613953 | 0.80 | CXCR4 (0.65) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL17931046 | 0.80 | CXCR4 (0.55) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL29863134 | 0.79 | LMNA (0.84) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL14818737 | 0.79 | LMNA (0.84) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL19457135 | 0.78 | LMNA (0.54) | CXCR4CHRM2LMNACYP1A2CYP2D6 | |
| SCHEMBL2008758 | 0.77 | CXCR4 (0.56) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL21610014 | 0.75 | CXCR4 (1.00) | CXCR4CHRM2MEN1CHRM1ADRA2C | |
| SCHEMBL673928 | 0.75 | CXCR4 (0.63) | CXCR4CHRM2MEN1CHRM1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223166-A1 | Linked cyclic polyamines with activity against hiv. | AnorMED Inc. (CA) | 2002-07-17 | — | — | EP | claimed |