Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.51 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MTTP | P55157 | 4/20 | 0.51 |
| ▸ | APOB | P04114 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607886 | 0.91 | EPHX2 (0.58) | KMT2AEPHX2RXFP1MEN1MTTP | |
| SCHEMBL7605675 | 0.90 | HTT (0.72) | KMT2AHTTMAPTSMN1; SMN2TSHR | |
| SCHEMBL7612180 | 0.90 | MTTP (0.61) | HTTRXFP1MTTPAPOBALDH1A1 | |
| SCHEMBL7613634 | 0.89 | ROCK2 (0.56) | RXFP1MTTPAPOBCSF1R | |
| SCHEMBL7607440 | 0.89 | MTTP (0.57) | HTTMTTPAPOBALDH1A1LMNA | |
| SCHEMBL7605521 | 0.88 | RXFP1 (0.55) | EPHX2RXFP1MTTPAPOBNAMPT | |
| SCHEMBL6792347 | 0.86 | NAMPT (0.54) | KMT2AHTTEPHX2RXFP1MEN1 | |
| SCHEMBL7605581 | 0.86 | SENP1 (0.59) | HTTRXFP1MTTPAPOBALDH1A1 | |
| SCHEMBL7606402 | 0.86 | MTTP (0.57) | HTTRXFP1MTTPAPOBALDH1A1 | |
| SCHEMBL7609363 | 0.86 | MTTP (0.57) | HTTRXFP1MTTPAPOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | KMT2A 2379/4885HTT 3107/4885EPHX2 1348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.