SCHEMBL6792347

SCHEMBL6792347

O=C(NCc1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)cc1)c1cccnc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.54
MTTP P55157 6/20 0.53
KMT2A Q03164 2/20 0.53
HTT P42858 1/20 0.53
KDR P35968 1/20 0.52
MEN1 O00255 1/20 0.51
APOB P04114 1/20 0.51
TSHR P16473 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
HIF1A Q16665 1/20 0.49
EPAS1 Q99814 1/20 0.49
KDM1A O60341 1/20 0.49
HDAC1 Q13547 1/20 0.49
TRPV1 Q8NER1 1/20 0.49
EPHX2 P34913 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7607886 0.94 EPHX2 (0.58) NAMPTMTTPKMT2AMEN1APOB
SCHEMBL6788420 0.91 MTTP (0.57) NAMPTMTTPKDRAPOBKDM1A
SCHEMBL7605521 0.86 RXFP1 (0.55) NAMPTMTTPKDRAPOBRXFP1
SCHEMBL7608638 0.86 KMT2A (0.58) NAMPTMTTPKMT2AHTTMEN1
SCHEMBL7608096 0.85 ROCK2 (0.50) NAMPTMTTPKDRAPOBKDM1A
SCHEMBL7041940 0.84 KDM1A (0.56) NAMPTMTTPAPOBKDM1AHDAC1
SCHEMBL7613634 0.84 ROCK2 (0.56) MTTPKDRAPOBRXFP1KDM1A
SCHEMBL7613600 0.84 MTTP (0.58) NAMPTMTTPAPOBRXFP1EPHX2
SCHEMBL7607440 0.83 MTTP (0.57) MTTPHTTAPOBKDM1AHDAC1
SCHEMBL6798640 0.83 HIF1A (0.53) NAMPTMTTPKMT2AHTTKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 NAMPT 1407/4885MTTP 363/4885KMT2A 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.