Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489676 | 0.90 | ALDH1A1 (0.47) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL7845387 | 0.87 | ALDH1A1 (0.46) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL7846325 | 0.84 | ALDH1A1 (0.44) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL7491803 | 0.84 | ALDH1A1 (0.44) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL7608728 | 0.83 | KMT2A (0.38) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL27976888 | 0.77 | ALDH1A1 (0.41) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL3812812 | 0.77 | ALDH1A1 (0.43) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL9381103 | 0.77 | LMNA (0.50) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL499644 | 0.76 | ALDH1A1 (0.68) | ALDH1A1DRD3KDM4EHPGDHSD17B10 | |
| SCHEMBL501895 | 0.76 | DRD3 (0.68) | ALDH1A1DRD3KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432948-B1 | ANTIULCER AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-13 | — | — | US | disclosed |
| EP-0946176-B1 | THE USE OF 7-(2-OXA-5,8-DIAZABICYCLO 4.3.0]NON-8-YL)-QUINOLONE CARBOXYLIC ACID AND NAPHTHYRIDON CARBOXYLIC ACID DERIVATIVES FOR MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF HELICOBACTER PYLORI INFECTIONS AND ASSOCIATED GASTRODUODENAL DISEASES | BAYER AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6133260-A | Use of 7-(2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-quinolone carboxylic acid and naphthyridon carboxylic acid derivatives for the treatment of Helicobacter pylori infections and associated gastroduodenal diseases | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | disclosed |