SCHEMBL7608797

SCHEMBL7608797

C[Si](C)(C)OC(=O)c1ccccc1O[Si](C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.41
KDM4E B2RXH2 2/20 0.41
SLC6A3 Q01959 2/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
KMT2A Q03164 5/20 0.40
HTT P42858 1/20 0.40
ELANE P08246 1/20 0.40
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 4/20 0.38
ESR1 P03372 2/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38
HMGB1 P09429 1/20 0.38
GGT1 P19440 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30420964 1.00 HSD17B10 (0.41) HSD17B10KDM4ESLC6A3LMNACYP1A2
SCHEMBL8201911 0.85 SLC6A3 (0.57) HSD17B10KDM4ESLC6A3LMNAKMT2A
SCHEMBL16004864 0.84 TSHR (0.50) HSD17B10KDM4ELMNAALDH1A1L3MBTL1
SCHEMBL10888889 0.82 ELANE (0.56) HSD17B10KDM4ELMNAKMT2AHTT
SCHEMBL1005499 0.82 HSD17B10 (0.39) HSD17B10KDM4ESLC6A3LMNACYP1A2
Potassium SCHEMBL30901224 0.82 TSHR (0.48) HSD17B10KDM4ELMNAALDH1A1L3MBTL1
SCHEMBL7542033 0.81 KDM4E (0.58) HSD17B10KDM4ELMNACYP1A2CYP2C9
SCHEMBL8832076 0.81 LMNA (0.53) HSD17B10KDM4ELMNAKMT2AHTT
SCHEMBL11089497 0.80 KCNK3 (0.47) ALDH1A1L3MBTL1
SCHEMBL30949873 0.79 CA12 (0.38) KDM4ECYP1A2KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112684070-B Method for measuring semi-volatile organic compounds in solid waste 山东微谱检测技术有限公司 2024-05-24 CN disclosed
CN-116615172-A Composition comprising a natural polymer and one or more (bio) alkanediols 西姆莱斯股份公司 2023-08-18 CN disclosed
EP-1071431-A4 NOVEL DELIVERY OF HYDROXY CARBOXYLIC ACIDS CLARIANT LSM ITALIA SPA (US) 2002-03-13 EP disclosed
EP-1071431-A1 NOVEL DELIVERY OF HYDROXY CARBOXYLIC ACIDS PCR, INC. (US) 2001-01-31 EP disclosed
WO-1999045933-A9 NOVEL DELIVERY OF HYDROXY CARBOXYLIC ACIDS PCR (US) 1999-11-18 WO disclosed
WO-1999045933-A1 NOVEL DELIVERY OF HYDROXY CARBOXYLIC ACIDS PCR, INC. (US) 1999-09-16 WO disclosed
EP-0283775-B1 Use of capping agents to improve the stability of polyphenylene ether to oxidative degradation. GEN ELECTRIC (US) 1994-06-22 EP disclosed
EP-0043630-B1 IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS GIST-BROCADES N.V. (NL) 1986-01-08 EP disclosed
US-4400509-A WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST GIST-BROCADES N.V. (NL) 1983-08-23 US disclosed
EP-0043630-A2 Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds GIST-BROCADES N.V. (NL) 1982-01-13 EP disclosed