SCHEMBL7608902

SCHEMBL7608902

C=CCc1ccc(C(c2ccc(CC=C)c(CC=C)c2)(C(F)(F)F)C(F)(F)F)cc1CC=C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9617378 0.93 GABRA1 (0.39) ESR1ESR2GABRA1GABRB2POLB
SCHEMBL29414940 0.84 GABRA1 (0.56) ESR1ESR2GABRA1GABRB2POLB
SCHEMBL29463283 0.84 GABRA1 (0.56) ESR1ESR2GABRA1GABRB2POLB
SCHEMBL1055347 0.84 GABRA1 (0.56) ESR1ESR2GABRA1GABRB2POLB
SCHEMBL10039388 0.84 GABRA1 (0.36) ESR1ESR2GABRA1GABRB2NR1H2
SCHEMBL2300766 0.79 ESR1 (0.53) ESR1ESR2GABRA1GABRB2POLB
SCHEMBL16255461 0.78 PTGDR (0.41) GABRA1GABRB2
2-Allylphenol SCHEMBL22207670 0.78 GABRA1 (0.49) ESR1ESR2GABRA1GABRB2POLB
SCHEMBL9472337 0.77 GABRA1 (0.37) GABRA1GABRB2POLB
SCHEMBL16393687 0.77 ELANE (0.35) GABRA1GABRB2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002097168-A METHOD FOR PRODUCING AROMATIC TETRACARBOXYLIC ACID NEW JAPAN CHEM CO LTD 2002-04-02 JP disclosed
JP-2002097185-A METHOD FOR PRODUCING AROMATIC TETRACARBOXYLIC DIANHYDRIDE NEW JAPAN CHEM CO LTD 2002-04-02 JP disclosed