SCHEMBL7609167

SCHEMBL7609167

CCc1ccccc1-c1c(C(C)C)cc(C(C)C)cc1C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 2/20 0.41
FABP4 P15090 2/20 0.41
FABP5 Q01469 1/20 0.41
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
CSNK2A3 Q8NEV1 1/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
NR3C1 P04150 1/20 0.34
HTT P42858 1/20 0.34
TRPA1 O75762 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16050486 0.77 FABP3 (0.41) FABP3FABP4FABP5LMNAALDH1A1
SCHEMBL28438073 0.77 GABRA1 (0.38) FABP3FABP4FABP5LMNAMAPT
SCHEMBL28926436 0.77 LMNA (0.44) FABP3FABP4FABP5LMNANPC1
SCHEMBL20862831 0.76 FABP3 (0.33) FABP3FABP4FABP5GABRA1GABRB2
SCHEMBL27920699 0.76 GABRA1 (0.35) FABP3FABP4FABP5GABRA1GABRB2
SCHEMBL30932846 0.76 CA1 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL7609162 0.75 LMNA (0.32) CSNK2A2CSNK2BCSNK2A1CSNK2A3LMNA
SCHEMBL366622 0.75 GABRA1 (0.37) FABP3FABP4FABP5LMNAGABRA1
SCHEMBL366603 0.75 GABRA1 (0.37) FABP3FABP4FABP5LMNAGABRA1
SCHEMBL7715672 0.75 GABRA1 (0.50) FABP3FABP4FABP5LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785967-B1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SC HOLDING AG (CH) 2002-01-09 EP disclosed
US-5807932-A USING A HYDROXYPHENYLALKYLPHOSPHORIC ESTER CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
WO-1996011978-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-04-25 WO disclosed