SCHEMBL7609162

SCHEMBL7609162

CCc1ccccc1-c1c(C(C)C)[c]c(C(C)C)cc1C(C)C

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.32
DPP4 P27487 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
CSNK2A3 Q8NEV1 1/20 0.32
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KMT2A Q03164 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7609167 0.75 FABP3 (0.41) LMNACSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL30932846 0.69 CA1 (0.43) LMNADPP4NR1H2NR1H3CSNK2A2
SCHEMBL28684935 0.66 TRPA1 (0.40) LMNACSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL11654644 0.64 GABRA1 (0.46) LMNAALDH1A1MAPTL3MBTL1
SCHEMBL545484 0.64 GABRA1 (0.46) LMNAMAPTL3MBTL1
SCHEMBL29657207 0.64 GABRA1 (0.46) LMNAMAPTL3MBTL1
SCHEMBL1133085 0.64 PDK2 (0.49) LMNADPP4CSNK2A2CSNK2BCSNK2A1
SCHEMBL5710969 0.64 CA1 (0.39) LMNADPP4NR1H2NR1H3TRPA1
SCHEMBL6546352 0.64 DPP4 (0.37) LMNADPP4NR1H2NR1H3CSNK2A2
SCHEMBL18007602 0.64 LMNA (0.33) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785967-B1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SC HOLDING AG (CH) 2002-01-09 EP disclosed
US-5807932-A USING A HYDROXYPHENYLALKYLPHOSPHORIC ESTER CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
WO-1996011978-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-04-25 WO disclosed