SCHEMBL7609581

SCHEMBL7609581

CCc1cccc(N2C(=O)C=CC2=O)c1C

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.72
TLR9 Q9NR96 1/20 0.52
TSHR P16473 1/20 0.46
FAAH O00519 2/20 0.44
HSP90AA1 P07900 1/20 0.42
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510771 0.84 MGLL (1.00) MGLLTLR9TSHRFAAHHSP90AA1
SCHEMBL1535499 0.84 MGLL (1.00) MGLLTLR9TSHRFAAHHSP90AA1
SCHEMBL144793 0.84 MGLL (0.65) MGLLTLR9FAAHHSP90AA1
SCHEMBL5086724 0.81 MGLL (0.72) MGLLTLR9TSHRFAAHHSP90AA1
SCHEMBL8766123 0.79 KDM5A (0.49) MGLLTSHRLMNAMAPT
SCHEMBL710771 0.79 MGLL (0.70) MGLLTLR9TSHRFAAHHSP90AA1
SCHEMBL29440938 0.79 MGLL (0.70) MGLLTLR9TSHRFAAHHSP90AA1
SCHEMBL27593915 0.76 MGLL (0.82) MGLLTLR9TSHRFAAHHSP90AA1
SCHEMBL331144 0.76 MGLL (0.64) MGLLTLR9FAAHHSP90AA1PTGS1
SCHEMBL9172497 0.76 MGLL (0.66) MGLLTLR9FAAHHSP90AA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0726252-B1 Process for the preparation of N-substituted cyclic imides BAYER AG (DE) 2002-04-17 EP disclosed
EP-0726252-A1 Process for the preparation of N-substituted cyclic imides BAYER AG (DE) 1996-08-14 EP disclosed