Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634441 | 0.87 | FAAH (0.54) | FAAHMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28389774 | 0.80 | MAPT (0.58) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5054488 | 0.77 | SMN1; SMN2 (0.50) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5053364 | 0.76 | SMN1; SMN2 (0.49) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL7605396 | 0.75 | ACP3 (0.63) | MEN1KMT2AMAPTCYP3A4TDP1 | |
| SCHEMBL8520179 | 0.74 | SRC (0.39) | FAAHMEN1KMT2AMAPTSMN1; SMN2 | |
| Phosphoric Acid SCHEMBL22235321 | 0.73 | MEN1 (0.58) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL13619243 | 0.73 | MEN1 (0.53) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL3836998 | 0.71 | SRC (0.57) | MEN1KMT2AHPGDTDP1L3MBTL1 | |
| SCHEMBL2003499 | 0.71 | MAPT (0.68) | FAAHMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514184-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |