Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920954 | 0.78 | KDM4E (0.44) | HSD17B10KDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5198345 | 0.77 | L3MBTL1 (0.54) | HSD17B10KDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL19356924 | 0.75 | MAPT (0.46) | HSD17B10KDM4EALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL6225917 | 0.75 | KDM4E (0.48) | HSD17B10KDM4EHPGDALDH1A1L3MBTL1 | |
| SCHEMBL27601386 | 0.73 | HSD17B10 (0.52) | HSD17B10KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL9196259 | 0.73 | CYP1A2 (0.53) | KDM4EALDH1A1CYP1A2MAPTGAA | |
| SCHEMBL9196304 | 0.73 | KMT2A (0.54) | KDM4EHPGDALDH1A1CYP1A2MAPT | |
| SCHEMBL9194034 | 0.73 | LMNA (0.56) | KDM4EALDH1A1L3MBTL1CYP1A2LMNA | |
| SCHEMBL18196544 | 0.72 | HSD17B10 (0.54) | HSD17B10KDM4EHPGDALDH1A1PIM1 | |
| SCHEMBL3985855 | 0.72 | KDM4E (0.46) | HSD17B10KDM4EHPGDALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778844-B1 | FUNCTIONAL TERPYRIDINE METAL COMPLEXES, METHODS FOR THEIR PREPARATION AND OLIGONUCLEOTIDE CONJUGATES WITH TERPYRIDINE METAL COMPLEXES | NOVARTIS AG (CH) | 2002-12-18 | — | — | EP | disclosed |
| EP-0778845-A1 | OLIGONUCLEOTIDE CONJUGATES, COMPOSITIONS AND METHODS FOR SPLITTING RIBONUCLEIC ACIDS | Novartis AG (CH) | 1997-06-18 | — | — | EP | disclosed |
| EP-0778844-A1 | FUNCTIONAL TERPYRIDINE METAL COMPLEXES, METHODS FOR THEIR PREPARATION AND OLIGONUCLEOTIDE CONJUGATES WITH TERPYRIDINE METAL COMPLEXES | Novartis AG (CH) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996007668-A1 | FUNCTIONAL TERPYRIDINE METAL COMPLEXES, METHODS FOR THEIR PREPARATION AND OLIGONUCLEOTIDE CONJUGATES WITH TERPYRIDINE METAL COMPLEXES | NOVARTIS AG (CH) | 1996-03-14 | — | — | WO | disclosed |
| WO-1996007667-A1 | OLIGONUCLEOTIDE CONJUGATES, COMPOSITIONS AND METHODS FOR SPLITTING RIBONUCLEIC ACIDS | NOVARTIS AG (CH) | 1996-03-14 | — | — | WO | disclosed |