Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196304 | 0.85 | KMT2A (0.54) | CYP1A2ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9194034 | 0.85 | LMNA (0.56) | CYP1A2ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9191091 | 0.83 | ALDH1A1 (0.48) | CYP1A2ALDH1A1KDM4EPDE2ASMN1; SMN2 | |
| SCHEMBL8720788 | 0.81 | CYP1A2 (0.56) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL423183 | 0.79 | PDE2A (0.61) | CYP1A2ALDH1A1KDM4EPDE2ASMN1; SMN2 | |
| SCHEMBL7008162 | 0.75 | EDNRB (0.48) | CYP1A2ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9196695 | 0.75 | LMNA (0.45) | CYP1A2ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9423136 | 0.74 | ALDH1A1 (0.56) | CYP1A2ALDH1A1KDM4EPDE2ASMN1; SMN2 | |
| SCHEMBL7609731 | 0.73 | HSD17B10 (0.42) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9196191 | 0.73 | MTNR1A (0.38) | CYP1A2ALDH1A1KDM4ESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497851-B1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-01-04 | — | — | EP | disclosed |
| WO-1991006541-A1 | SULPHONATED HETEROCYCLIC CARBOXAMIDES AS HERBICIDES, GROWTH REGULATORS OR FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-16 | — | — | WO | disclosed |