Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611013 | 0.85 | CYP17A1 (0.46) | SMN1; SMN2HPGDRAB9ANPC1L3MBTL1 | |
| SCHEMBL7610612 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| Propionic Acid SCHEMBL27745596 | 0.80 | FFAR1 (0.46) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL7609937 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL7612463 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL416523 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1LMNA | |
| SCHEMBL7027861 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL9601863 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9609808 | 0.75 | SMN1; SMN2 (0.82) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL24333940 | 0.75 | LMNA (0.43) | HPGDMAPTALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |