Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609839 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7610612 | 0.78 | SMN1; SMN2 (0.56) | SMN1; SMN2HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL13999161 | 0.78 | MEN1 (0.39) | SMN1; SMN2MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL8000580 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7612463 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7609942 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL1856703 | 0.75 | CYP17A1 (0.45) | — | |
| SCHEMBL7027861 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7516303 | 0.73 | CA12 (0.46) | SMN1; SMN2PKM | |
| SCHEMBL9609808 | 0.73 | SMN1; SMN2 (0.82) | SMN1; SMN2HPGDMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |