Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609937 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL25223968 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL10161781 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTALDH1A1GAANPC1 | |
| SCHEMBL8000580 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL27552518 | 0.71 | SIGMAR1 (0.40) | ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28476992 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL3901283 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL8366738 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL8741875 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL1022686 | 0.70 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |