Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7609958

CSc1cccc(C)c1SC.N.N.N.N

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.36
CYP1A2 P05177 1/20 0.36
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
ACHE P22303 1/20 0.35
ALDH1A1 P00352 5/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
SCN4A P35499 4/20 0.34
MAPT P10636 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
GRM5 P41594 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
KMT2A Q03164 1/20 0.32
TRPA1 O75762 2/20 0.31
CD44 P16070 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL6855349 1.00 CYP2A6 (0.36) CYP2A6CYP1A2LMNATSHRACHE
Ammonia Solution, Strong SCHEMBL4446667 1.00 CYP2A6 (0.36) CYP2A6CYP1A2LMNATSHRACHE
SCHEMBL2320126 0.98 CYP2A6 (0.38) CYP2A6CYP1A2LMNATSHRACHE
SCHEMBL28762438 0.86 LMNA (0.37) CYP2A6CYP1A2LMNATSHRACHE
Ammonia Solution, Strong SCHEMBL16781733 0.85 ALDH1A1 (0.33) LMNAALDH1A1MAPTL3MBTL1GRM5
SCHEMBL4460481 0.82 CYP2A6 (0.45) CYP2A6CYP1A2TSHRACHEALDH1A1
SCHEMBL18378891 0.82 ALDH1A1 (0.34) LMNAALDH1A1MAPTL3MBTL1GRM5
Ammonia Solution, Strong SCHEMBL16781740 0.78 ALDH1A1 (0.32) TSHRALDH1A1
Ammonia Solution, Strong SCHEMBL12275367 0.77 ACHE (0.47) LMNATSHRACHEALDH1A1CA1
SCHEMBL6735223 0.76 CYP2A6 (0.36) CYP2A6CYP1A2LMNATSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705287-B1 POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE ASHLAND OIL INC (US) 2002-10-16 EP disclosed
US-5548056-A FOR FIBERGLASS REINFORCED POLYESTER ASHLAND INC. (US) 1996-08-20 US disclosed
EP-0705287-A1 POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE ASHLAND OIL, INC. (US) 1996-04-10 EP disclosed
EP-0705287-A4 POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE ASHLAND OIL INC (US) 1995-06-20 EP disclosed
WO-1993018074-A1 POLYUREAURETHANE PRIMERLESS STRUCTURAL ADHESIVE ASHLAND OIL, INC. (US) 1993-09-16 WO disclosed