Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 8/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605577 | 0.84 | HSD17B10 (0.53) | PDE7ATXNRD1TXNRD3TXNRD2HSD17B10 | |
| SCHEMBL7605576 | 0.83 | PDE7A (0.48) | PDE7ATXNRD1TXNRD3TXNRD2HSD17B10 | |
| SCHEMBL7606524 | 0.81 | PDE7A (0.54) | PDE7ATXNRD1TXNRD3TXNRD2HSD17B10 | |
| SCHEMBL29563911 | 0.79 | HSD17B10 (0.60) | PDE7AHSD17B10RORC | |
| SCHEMBL1148427 | 0.79 | HSD17B10 (0.60) | PDE7AHSD17B10RORC | |
| SCHEMBL27895137 | 0.78 | PDE7A (0.73) | PDE7ATXNRD1TXNRD3TXNRD2PDE4B | |
| Selenium SCHEMBL10605380 | 0.78 | HSD17B10 (0.58) | PDE7AHSD17B10RORC | |
| SCHEMBL7606300 | 0.78 | TSHR (0.53) | PDE7A | |
| SCHEMBL3207733 | 0.76 | AR (0.53) | PDE7AAR | |
| SCHEMBL7610002 | 0.75 | PDE7A (0.59) | PDE7ATXNRD1TXNRD3TXNRD2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165504-A2 | INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF | ICOS CORPORATION (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059878-A2 | INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF | ICOS CORPORATION (US) | 2000-10-12 | — | — | WO | disclosed |