SCHEMBL7610539

SCHEMBL7610539

CCCCCCCCCCCCCCCCC(C)(O)[CH]O

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 10/20 0.43
GGPS1 O95749 7/20 0.43
SMPD1 P17405 1/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
CES2 O00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15333382 0.83 FDPS (0.45) FDPSGGPS1SMPD1TSHRTHRB
SCHEMBL15333380 0.83 FDPS (0.45) FDPSGGPS1SMPD1TSHRTHRB
SCHEMBL270891 0.79
SCHEMBL2368497 0.79 ALOX15 (0.50) FDPSGGPS1TSHR
SCHEMBL11662678 0.79 FDPS (0.42) FDPSGGPS1SMPD1CES2
SCHEMBL4428879 0.79 ALOX15 (0.50) FDPSGGPS1TSHR
SCHEMBL29135504 0.79 FDPS (0.42) FDPSGGPS1SMPD1CES2
SCHEMBL4591909 0.79 ALOX15 (0.50) FDPSGGPS1TSHR
SCHEMBL9306274 0.79 ALOX15 (0.50) FDPSGGPS1TSHR
SCHEMBL11661851 0.79 FDPS (0.42) FDPSGGPS1SMPD1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202750-A4 METHOD OF TREATING HIV INFECTION AND RELATED SECONDARY INFECTIONS THEREOF BURCOGLU ARSINUR (US) 2002-10-16 EP disclosed
EP-1202750-A1 METHOD OF TREATING HIV INFECTION AND RELATED SECONDARY INFECTIONS THEREOF BURCOGLU, Arsinur (US) 2002-05-08 EP disclosed
WO-1998048843-A1 METHOD OF TREATING HIV INFECTION AND RELATED SECONDARY INFECTIONS THEREOF BURCOGLU ARSINUR (US) 1998-11-05 WO disclosed