Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610763 | 0.86 | RAB9A (0.47) | RAB9AKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL20442339 | 0.81 | RAB9A (0.78) | RAB9AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL8669488 | 0.80 | RAB9A (0.69) | RAB9AKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL8130235 | 0.79 | RAB9A (0.67) | RAB9AKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL27471805 | 0.75 | RAB9A (0.76) | RAB9AKMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8683973 | 0.74 | RAB9A (0.75) | RAB9AKMT2AMEN1ALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL27455337 | 0.74 | RAB9A (0.74) | RAB9AKMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7617782 | 0.73 | GAA (0.39) | RAB9AKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL3634188 | 0.72 | ALDH1A1 (0.80) | RAB9AKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL16350948 | 0.72 | RAB9A (0.67) | RAB9AKMT2AMEN1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739903-B1 | CARBAMOYLMETHYLUREA DERIVATIVE | SHIONOGI & CO (JP) | 2002-01-23 | — | — | EP | disclosed |
| US-5739162-A | ANTAGONIST FOR GASTRIN AND/OR CHOLECYSTOKININ B-NOT A-RECEPTORS; SIDE EFFECT REDUCTION; ANTIULCER AGENTS; OPIOD-ENHANCING ANALGESICS; GASTROINTESTINAL DISORDERS; ANXIOLYTIC AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0739903-A1 | CARBAMOYLMETHYLUREA DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |