Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PPIA | P62937 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20442339 | 0.88 | RAB9A (0.78) | RAB9AMAPTKMT2ASLC6A2SLC6A3 | |
| SCHEMBL8130235 | 0.86 | RAB9A (0.67) | RAB9AMAPTKMT2ASLC6A2SLC6A3 | |
| SCHEMBL8683968 | 0.85 | NAMPT (0.65) | RAB9AMAPTTHRBKMT2ANAMPT | |
| SCHEMBL8686196 | 0.83 | CASR (0.65) | RAB9AMAPTKMT2ACASRNPC1 | |
| SCHEMBL27471805 | 0.82 | RAB9A (0.76) | RAB9AMAPTKMT2ASLC6A2SLC6A3 | |
| SCHEMBL7610708 | 0.81 | NAMPT (0.47) | RAB9AMAPTTHRBKMT2ANAMPT | |
| SCHEMBL8683973 | 0.81 | RAB9A (0.75) | RAB9AMAPTTHRBKMT2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL27455337 | 0.81 | RAB9A (0.74) | RAB9AMAPTKMT2ASLC6A2SLC6A3 | |
| SCHEMBL8870336 | 0.81 | NAMPT (0.52) | RAB9AMAPTTHRBKMT2ANAMPT | |
| SCHEMBL7610643 | 0.80 | RAB9A (0.58) | RAB9AMAPTTHRBKMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716936-A | Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders | RHONE-POULENC RORER S.A. (FR) | 1998-02-10 | — | — | US | disclosed |
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |
| US-5624939-A | N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders | RHONE-POULENC RORER, S.A. (FR) | 1997-04-29 | — | — | US | disclosed |
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |