Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 6/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22577684 | 0.84 | HRH1 (0.44) | HRH1HRH2 | |
| SCHEMBL7604209 | 0.82 | USP2 (0.43) | SMN1; SMN2USP2 | |
| SCHEMBL21068880 | 0.80 | TSHR (0.47) | HRH1DRD2SMN1; SMN2HRH2KDM4E | |
| SCHEMBL20745447 | 0.80 | HSD11B1 (0.47) | DRD3HSD11B1DRD2KCNA5TDP1 | |
| SCHEMBL16758742 | 0.80 | HSD11B1 (0.47) | DRD3HSD11B1DRD2KCNA5TDP1 | |
| SCHEMBL7604063 | 0.80 | TACR1 (0.40) | HRH1DRD3HSD11B1KCNA5SLC6A2 | |
| SCHEMBL17847599 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4E | |
| SCHEMBL31286711 | 0.79 | SCN9A (0.44) | HRH1DRD2SMN1; SMN2SLC29A1 | |
| SCHEMBL3052320 | 0.79 | HSD11B1 (0.55) | DRD3HSD11B1DRD2KCNA5TDP1 | |
| SCHEMBL12120192 | 0.79 | TDP1 (0.51) | SMN1; SMN2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | claimed |
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | disclosed |
| EP-0927173-A1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB, S.A. (BE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1997037982-A1 | NOVEL SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB S.A. (BE) | 1997-10-16 | — | — | WO | disclosed |