Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710700 | 0.82 | L3MBTL1 (0.53) | TACR1L3MBTL1MEN1KMT2A | |
| SCHEMBL7609141 | 0.81 | HRH2 (0.49) | HRH1HRH2 | |
| SCHEMBL4709553 | 0.80 | L3MBTL1 (0.57) | L3MBTL1MEN1KMT2A | |
| SCHEMBL7611072 | 0.80 | HRH1 (0.41) | KCNA5HRH1DRD3SLC6A2HRH2 | |
| SCHEMBL7605519 | 0.80 | TLR8 (0.46) | USP2 | |
| SCHEMBL21855434 | 0.79 | SIGMAR1 (0.39) | LTA4HKCNA5TDP1TEAD3SIGMAR1 | |
| SCHEMBL3553321 | 0.79 | NAMPT (0.44) | KCNA5HRH1DRD3HRH2HTR2A | |
| SCHEMBL22577684 | 0.78 | HRH1 (0.44) | HRH1HRH2 | |
| SCHEMBL22266212 | 0.77 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2A | |
| SCHEMBL7603566 | 0.77 | MEN1 (0.44) | HRH1HRH2TDP1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | claimed |
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | disclosed |
| EP-0927173-A1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB, S.A. (BE) | 1999-07-07 | — | — | EP | disclosed |
| WO-1997037982-A1 | NOVEL SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB S.A. (BE) | 1997-10-16 | — | — | WO | disclosed |