Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 2/20 | 0.64 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059962 | 0.83 | AKR1B1 (0.67) | P2RX1TMPRSS4HPGDLMNAMLYCD | |
| SCHEMBL13812674 | 0.78 | TMPRSS4 (1.00) | P2RX1TMPRSS4HPGDLMNAMLYCD | |
| SCHEMBL7066268 | 0.78 | AKR1B1 (0.62) | P2RX1TMPRSS4HPGDLMNAAKR1B1 | |
| SCHEMBL3281999 | 0.74 | RHOC (0.56) | P2RX1TMPRSS4CYP2C19MEN1CYP1A2 | |
| SCHEMBL7063092 | 0.74 | AKR1B1 (0.67) | HPGDLMNACYP2C19AKR1B1CCR1 | |
| SCHEMBL130511 | 0.73 | TMPRSS4 (0.65) | P2RX1TMPRSS4CYP2C19ALDH1A1MEN1 | |
| SCHEMBL16088678 | 0.73 | P2RX1 (0.57) | P2RX1TMPRSS4HPGDLMNAMLYCD | |
| SCHEMBL13812913 | 0.72 | TMPRSS4 (0.86) | P2RX1TMPRSS4HPGDLMNACYP2C19 | |
| SCHEMBL16128007 | 0.71 | P2RX1 (0.55) | P2RX1TMPRSS4HPGDLMNAMLYCD | |
| SCHEMBL5943436 | 0.71 | ALDH1A1 (0.60) | HPGDCYP2C19KDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198451-A2 | SUBSTITUTED PHENOXYACETIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001000566-A2 | SUBSTITUTED PHENOXYACETIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-01-04 | — | — | WO | disclosed |