Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965847 | 0.78 | PRKCA (0.47) | GLS2PRKCA | |
| SCHEMBL764405 | 0.74 | PRKCA (0.42) | GLS2PRKCA | |
| SCHEMBL9787814 | 0.73 | CHRM1 (0.42) | — | |
| SCHEMBL23945692 | 0.72 | KDM4C (0.43) | — | |
| SCHEMBL4922117 | 0.72 | TSHR (0.39) | TRPV1PRKCA | |
| SCHEMBL4930526 | 0.72 | TSHR (0.39) | TRPV1PRKCA | |
| SCHEMBL4922132 | 0.72 | TSHR (0.39) | TRPV1PRKCA | |
| SCHEMBL1116238 | 0.71 | — | — | |
| SCHEMBL7605158 | 0.71 | ALDH1A1 (0.38) | TRPV1 | |
| SCHEMBL11741768 | 0.70 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719267-B1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS INC (US) | 2002-07-31 | — | — | EP | disclosed |
| EP-0719267-A1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0719267-A4 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS INC (US) | 1996-02-16 | — | — | EP | disclosed |
| US-5470878-A | Cell signaling inhibitors | CELL THERAPEUTICS, INC. (US) | 1995-11-28 | — | — | US | disclosed |
| WO-1994022863-A9 | SECOND MESSENGER CELL SIGNALING INHIBITORS | — | 1994-12-22 | — | — | WO | disclosed |
| WO-1994022863-A1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |