Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | HBB | P68871 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29528582 | 1.00 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL25289019 | 0.98 | MAPT (0.56) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL1147541 | 0.87 | CYP1A2 (0.59) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3761409 | 0.85 | CYP1A2 (0.58) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL12196111 | 0.83 | CYP1A2 (0.51) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL378949 | 0.82 | SMN1; SMN2 (0.62) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL10064479 | 0.82 | MAPT (0.63) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL17460879 | 0.82 | MAPT (0.63) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL1920755 | 0.80 | NPC1 (0.60) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL2479413 | 0.78 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322132-B | N-substituted indole compound and synthesis method thereof | 陕西科技大学 | 2024-05-28 | — | — | CN | claimed |
| CN-115322132-A | N-substituted indole compound and synthetic method thereof | 陕西科技大学 | 2022-11-11 | — | — | CN | claimed |
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2009-01-22 | — | — | US | claimed |
| EP-1943217-A1 | COMPOUNDS COMPRISING A LACTAM OR A LACTAM DERIVATIVE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB Pharma, S.A. (BE) | 2008-07-16 | — | — | EP | claimed |
| WO-2007048595-A1 | COMPOUNDS COMPRISING A LACTAM OR A LACTAM DERIVATIVE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA, S.A. (BE) | 2007-05-03 | — | — | WO | claimed |
| EP-4619405-A1 | TSPO LIGANDS | The University Of Sydney (AU) | 2025-09-24 | — | — | EP | disclosed |
| CN-115322132-B | N-substituted indole compound and synthesis method thereof | 陕西科技大学 | 2024-05-28 | — | — | CN | disclosed |
| WO-2024103126-A1 | TSPO LIGANDS | THE UNIVERSITY OF SYDNEY (AU) | 2024-05-23 | — | — | WO | disclosed |
| US-20240065955-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND AN ALKYL(POLY)GLYCOSIDE | L'OREAL (FR) | 2024-02-29 | — | — | US | disclosed |
| US-20240024217-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A PARTICULAR OXYETHYLENATED FATTY ACID ESTER OF SORBITAN | L'ORÉAL (FR) | 2024-01-25 | — | — | US | disclosed |
| US-20240018139-A1 | NEW SMALL-MOLECULE COMPOUNDS FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTORS AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | S＆K THERAPEUTICS (KR) | 2024-01-18 | — | — | US | disclosed |
| CN-114316951-B | Cadmium-based two-dimensional hybridization perovskite long afterglow material, and preparation method and application thereof | 南京邮电大学 | 2023-12-22 | — | — | CN | disclosed |
| WO-2001012188-A1 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-02-22 | — | — | WO | disclosed |
| EP-1066039-A1 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | Cocensys, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999044612-A1 | SUBSTITUTED QUINAZOLINES AND ANALOGS AND THE USE THEREOF | COCENSYS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| CN-1171785-A | Pyrimidine derivatives | KOWA CO (JP) | 1998-01-28 | — | — | CN | disclosed |
| EP-0700396-A1 | PIPERIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-03-13 | — | — | EP | disclosed |
| US-5478845-A | Inhibit dopamine or 5-hydroxytryptamine receptor binding | NOVO NORDISK A/S (DK) | 1995-12-26 | — | — | US | disclosed |
| WO-1994027994-A1 | PIPERIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-12-08 | — | — | WO | disclosed |
| US-3950339-A | SUBSTITUTED-2-(PYRIMIDINYLTHIO)ACETAMIDOXIMES AND ACETONITRILES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018139-A1 | NEW SMALL-MOLECULE COMPOUNDS FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTORS AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | TLR9, TLR8, TLR3 | MAPT 3661/4885SMN1; SMN2 3393/4885ALDH1A1 4824/4885 |
| US-20090023708-A1 | Compounds Comprising a Lactam or a Lactam Derivative Moiety, Processes for Making Them, and Their Uses | COASY, FURIN, PEPD | MAPT 2347/4885SMN1; SMN2 3988/4885ALDH1A1 1149/4885 |
| US-20240065955-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND AN ALKYL(POLY)GLYCOSIDE | KRT18, PLOD2, PLOD3 | MAPT 860/4885SMN1; SMN2 4434/4885ALDH1A1 824/4885 |
| US-20240024217-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS AND A PARTICULAR OXYETHYLENATED FATTY ACID ESTER OF SORBITAN | ELOVL5, KRT18, SLC25A20 | MAPT 629/4885SMN1; SMN2 3898/4885ALDH1A1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.