Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164468 | 0.90 | CTSK (0.52) | CASP1CTSLCTSSCTSKCTSB | |
| SCHEMBL7175172 | 0.76 | CTSK (0.53) | CTSSSMN1; SMN2CTSKCTSBKDM4E | |
| SCHEMBL7167328 | 0.76 | CTSK (0.56) | CTSLCTSSSMN1; SMN2CTSKCTSB | |
| SCHEMBL7164688 | 0.75 | CTSK (0.55) | HDAC1HDAC6HDAC4CTSLCTSS | |
| SCHEMBL5935127 | 0.75 | CTSK (0.77) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7163217 | 0.75 | CTSK (0.56) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7160519 | 0.75 | CTSK (0.63) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7468069 | 0.74 | PPARG (0.64) | SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL7456009 | 0.74 | CTSL (0.47) | HDAC1CTSLCTSSSMN1; SMN2CTSK | |
| SCHEMBL7163444 | 0.70 | CA1 (0.61) | CASP1CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065230-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2002-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065230-A1 | Protease inhibitors | PRSS1, DNPEP, CTSZ | HDAC1 660/4885HDAC6 1947/4885HDAC4 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.