Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608227 | 0.88 | PTGS1 (0.40) | L3MBTL1RAB9ASMN1; SMN2LMNAEPOR | |
| SCHEMBL7608529 | 0.87 | FFAR1 (0.40) | ESR1L3MBTL1ALDH1A1NPC1MAPK1 | |
| SCHEMBL7608285 | 0.86 | ADRB3 (0.40) | ESR1L3MBTL1ALDH1A1NPC1MAPK1 | |
| SCHEMBL7609423 | 0.86 | ADRB3 (0.40) | ESR1L3MBTL1ALDH1A1NPC1MAPK1 | |
| SCHEMBL7610365 | 0.85 | AOC3 (0.40) | ALDH1A1NPC1RAB9AEPORMAPT | |
| SCHEMBL7611109 | 0.85 | AOC3 (0.40) | ALDH1A1NPC1RAB9AEPORMAPT | |
| SCHEMBL7611523 | 0.84 | L3MBTL1 (0.41) | ESR1L3MBTL1ALDH1A1NPC1MAPK1 | |
| SCHEMBL7606221 | 0.82 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2LMNATRPM8 | |
| SCHEMBL7611069 | 0.80 | MEN1 (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7606237 | 0.79 | NPC1 (0.39) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |