Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617308 | 0.99 | DRD2 (0.44) | DRD2HTR2ASMN1; SMN2NPY1RHTR7 | |
| SCHEMBL7615685 | 0.95 | DRD2 (0.43) | DRD2HTR2ANPY1RHTR7HTR1A | |
| SCHEMBL7615669 | 0.95 | DRD2 (0.43) | DRD2HTR2ANPY1RHTR7HTR1A | |
| SCHEMBL7610391 | 0.93 | DRD2 (0.43) | DRD2HTR2ASMN1; SMN2HTR7HTR1A | |
| SCHEMBL7617460 | 0.91 | DRD2 (0.45) | DRD2HTR2ASMN1; SMN2NPY1RHTR7 | |
| SCHEMBL7617302 | 0.91 | DRD2 (0.41) | DRD2HTR2ASMN1; SMN2HTR7HTR1A | |
| SCHEMBL7608654 | 0.90 | DRD2 (0.41) | DRD2HTR2ASMN1; SMN2HTR7HTR1A | |
| SCHEMBL7618168 | 0.90 | DRD2 (0.42) | DRD2HTR2ASMN1; SMN2HTR7HTR1A | |
| SCHEMBL7618619 | 0.90 | DRD2 (0.42) | DRD2HTR2ASMN1; SMN2HTR7HTR1A | |
| SCHEMBL7616570 | 0.89 | DRD2 (0.40) | DRD2HTR2ASMN1; SMN2HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |