Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.43 |
| ▸ | HTR2A | P28223 | 7/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615669 | 0.98 | DRD2 (0.43) | DRD2HTR2ANPY1RHTR7HTR1A | |
| SCHEMBL7617308 | 0.96 | DRD2 (0.44) | DRD2HTR2ANPY1RHTR7HTR1A | |
| SCHEMBL7611941 | 0.95 | DRD2 (0.44) | DRD2HTR2ANPY1RHTR7HTR1A | |
| SCHEMBL7618619 | 0.94 | DRD2 (0.42) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7618168 | 0.93 | DRD2 (0.42) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7617302 | 0.92 | DRD2 (0.41) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7608654 | 0.92 | DRD2 (0.41) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7610391 | 0.90 | DRD2 (0.43) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7615648 | 0.90 | CNR2 (0.40) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7610983 | 0.89 | DRD2 (0.39) | DRD2HTR2AHTR7HTR1AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |