Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608654 | 0.98 | DRD2 (0.41) | DRD2HTR2ALMNAMAPK1CNR2 | |
| SCHEMBL7615685 | 0.92 | DRD2 (0.43) | DRD2HTR2ACNR2HTR7HTR1A | |
| SCHEMBL7615648 | 0.92 | CNR2 (0.40) | DRD2HTR2ALMNAMAPK1CNR2 | |
| SCHEMBL7615669 | 0.92 | DRD2 (0.43) | DRD2HTR2ACNR2HTR7HTR1A | |
| SCHEMBL7610983 | 0.92 | DRD2 (0.39) | DRD2HTR2ALMNAMAPK1CNR2 | |
| SCHEMBL7617308 | 0.91 | DRD2 (0.44) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7618619 | 0.91 | DRD2 (0.42) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7618168 | 0.91 | DRD2 (0.42) | DRD2HTR2AHTR7HTR1AHTR6 | |
| SCHEMBL7616570 | 0.91 | DRD2 (0.40) | DRD2HTR2ALMNAMAPK1CNR2 | |
| SCHEMBL7611941 | 0.91 | DRD2 (0.44) | DRD2HTR2ALMNAHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |