SCHEMBL761322

SCHEMBL761322

C[Si](C)(C)c1ccc(N(c2ccccc2)c2ccc3c(-c4ccc5cc6ccccc6cc5c4)c4cc(N(c5ccccc5)c5ccc([Si](C)(C)C)cc5)ccc4c(-c4ccc5cc6ccccc6cc5c4)c3c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 1/20 0.32
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
HSD17B10 Q99714 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL761290 0.96 IKBKB (0.35) IKBKBALDH1A1CYP1A2SMN1; SMN2HSD17B10
SCHEMBL762131 0.94 IKBKB (0.36) IKBKBALDH1A1CYP1A2SMN1; SMN2HSD17B10
SCHEMBL761300 0.93 CYP1A2 (0.36) IKBKBALDH1A1CYP1A2SMN1; SMN2HSD17B10
SCHEMBL760880 0.92 IKBKB (0.35) IKBKBALDH1A1CYP1A2SMN1; SMN2HSD17B10
SCHEMBL760858 0.91 ESR1 (0.35) ALDH1A1CYP1A2SMN1; SMN2HSD17B10KDM4E
SCHEMBL762479 0.89 IKBKB (0.33) IKBKBALDH1A1CYP1A2SMN1; SMN2HSD17B10
SCHEMBL762476 0.89 ESR1 (0.36) ALDH1A1CYP1A2SMN1; SMN2HSD17B10KDM4E
SCHEMBL14516031 0.86 GPR84 (0.34) IKBKBALDH1A1CYP1A2SMN1; SMN2HSD17B10
SCHEMBL760840 0.85 TDP1 (0.33) ALDH1A1CYP1A2KDM4EMEN1KMT2A
SCHEMBL14424845 0.85 ALDH1A3 (0.33) IKBKBALDH1A1CYP1A2SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8137823-B2 Anthracene derivatives, process for preparation thereof, and organic electronic light emitting device using the same LG CHEM, LTD. (KR) 2012-03-20 US disclosed
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090079334-A1 Novel Anthracene Derivatives, Process for Preparation Thereof, and Organic Electronic Light Emitting Device Using the Same XPOT, ALAD, APRT IKBKB 4465/4885ALDH1A1 434/4885CYP1A2 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.