Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 3/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859758 | 0.87 | HSD17B10 (0.42) | HSD17B10GAAKMT2AKDM4EHPGD | |
| SCHEMBL19940202 | 0.87 | HSD17B10 (0.46) | HSP90AA1HSD17B10GAAKMT2AKDM4E | |
| SCHEMBL2717847 | 0.86 | SMN1; SMN2 (0.43) | HSD17B10GAAKMT2AKDM4EHPGD | |
| SCHEMBL21518879 | 0.84 | HSD17B10 (0.43) | HSP90AA1HSD17B10GAAKMT2AKDM4E | |
| SCHEMBL9295787 | 0.80 | HSD17B10 (0.42) | HSD17B10GAAKMT2AKDM4EHPGD | |
| SCHEMBL9644750 | 0.80 | KDM4E (0.53) | KDM4EPKM | |
| SCHEMBL31575 | 0.80 | KDM4E (0.58) | HSD17B10GAAKMT2AKDM4EHPGD | |
| SCHEMBL3333926 | 0.78 | ALDH1A1 (0.50) | HSD17B10GAAKMT2AKDM4EHPGD | |
| SCHEMBL29706037 | 0.78 | CDC7 (0.47) | HSP90AA1HSD17B10GAAKMT2AKDM4E | |
| SCHEMBL2555611 | 0.78 | ALDH1A1 (0.41) | HSD17B10GAAKMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261579-A1 | DEHYDROAMINO ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001058853-A1 | DEHYDROAMINO ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-16 | — | — | WO | disclosed |