⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761454 | 0.88 | — | — | |
| SCHEMBL15942720 | 0.80 | KDM4E (0.31) | — | |
| SCHEMBL762285 | 0.79 | MEN1 (0.30) | — | |
| SCHEMBL761442 | 0.78 | KDM4E (0.30) | — | |
| SCHEMBL761449 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL16091822 | 0.74 | HTR3A (0.32) | — | |
| SCHEMBL16088864 | 0.73 | CHRNA7 (0.33) | — | |
| SCHEMBL676679 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL13212356 | 0.73 | CHRNA7 (0.34) | — | |
| SCHEMBL764512 | 0.72 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138202-B2 | Stable SNS-595 compositions and methods of preparation | SUNESIS PHARMACEUTICALS, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20110086876-A1 | STABLE SNS-595 COMPOSITIONS AND METHODS OF PREPARATION | SUNESIS PHARMACEUTICALS, INC. | 2011-04-14 | — | — | US | disclosed |