Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbetapentane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.84 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.84 |
| ▸ | LMNA | P02545 | 3/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.84 |
| ▸ | TSHR | P16473 | 3/20 | 0.84 |
| ▸ | PRCP | P42785 | 2/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.84 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.84 |
| ▸ | THRB | P10828 | 1/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.84 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.84 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caramiphen SCHEMBL1375563 | 0.95 | PRCP (0.84) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Caramiphen SCHEMBL158932 | 0.95 | PRCP (0.84) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Carbetapentane SCHEMBL67879 | 0.92 | CHRM2 (1.00) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Carbetapentane SCHEMBL15516338 | 0.92 | CHRM2 (1.00) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Carbetapentane SCHEMBL5174918 | 0.90 | CHRM2 (0.98) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Carbetapentane SCHEMBL15512243 | 0.89 | CHRM2 (0.95) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Caramiphen SCHEMBL181285 | 0.87 | PRCP (1.00) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Caramiphen SCHEMBL1374820 | 0.86 | ALDH1A1 (1.00) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Caramiphen SCHEMBL10898559 | 0.86 | PRCP (0.97) | CHRM2ALDH1A1CHRM1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL7383119 | 0.85 | ALDH1A1 (0.97) | CHRM2ALDH1A1CHRM1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235561-A2 | FAST DISSOLVING COMPOSITION WITH PROLONGED SWEET TASTE | Panacea Biotec Limited (IN) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001039749-A2 | FAST DISSOLVING COMPOSITION WITH PROLONGED SWEET TASTE | PANACEA BIOTEC LIMITED (IN) | 2001-06-07 | — | — | WO | disclosed |