Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487357 | 0.84 | PYCR1 (0.44) | POLBTP53MAPTPYCR1CYP1A2 | |
| SCHEMBL7614522 | 0.78 | CYP3A4 (0.43) | POLBMAPTRXFP1ALDH1A1MEN1 | |
| SCHEMBL30831861 | 0.77 | PYCR1 (0.36) | POLBTP53MAPTPYCR1FFAR4 | |
| SCHEMBL2807248 | 0.77 | PYCR1 (0.36) | POLBTP53MAPTPYCR1FFAR4 | |
| SCHEMBL5490805 | 0.75 | PYCR1 (0.40) | PYCR1ALDH1A1MAPK1 | |
| SCHEMBL8365116 | 0.74 | SMN1; SMN2 (0.41) | POLBTP53MAPTPYCR1CYP1A2 | |
| SCHEMBL2867783 | 0.74 | CA1 (0.38) | POLBTP53MAPTPYCR1FFAR4 | |
| SCHEMBL5481506 | 0.73 | — | — | |
| SCHEMBL2550855 | 0.72 | CYP2A6 (0.44) | POLBTP53MAPTPYCR1FFAR4 | |
| SCHEMBL21573669 | 0.72 | PYCR1 (0.36) | POLBTP53MAPTPYCR1SETDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |