Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529540 | 0.87 | MEN1 (0.52) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6744892 | 0.86 | KMT2A (0.56) | MEN1KMT2ANPSR1ALDH1A1L3MBTL1 | |
| SCHEMBL7614697 | 0.84 | PPARG (0.41) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7618868 | 0.83 | ACHE (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7528094 | 0.82 | NPC1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7250273 | 0.79 | KMT2A (0.53) | MEN1KMT2ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7242360 | 0.79 | MEN1 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27555232 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7529497 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7618948 | 0.76 | PPARG (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1195371-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-04-10 | — | — | EP | disclosed |