Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TAF1 | P21675 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743213 | 0.74 | BRD4 (0.31) | BRD4TAF1BRPF1CREBBPCECR2 | |
| SCHEMBL1913656 | 0.74 | — | — | |
| SCHEMBL8952367 | 0.72 | ADRA1D (0.33) | ALDH1A1KMT2AMEN1GPR84 | |
| SCHEMBL1923337 | 0.71 | CYP1A2 (0.44) | LMNAALDH1A1TSHRKDM4EKMT2A | |
| SCHEMBL27469859 | 0.69 | — | — | |
| SCHEMBL2586022 | 0.69 | — | — | |
| SCHEMBL8195724 | 0.69 | MAPK8 (0.35) | TSHRKDM4EBRD4MAPK8 | |
| SCHEMBL9118472 | 0.68 | KDM4E (0.39) | ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL28561589 | 0.68 | BRD4 (0.35) | KMT2AMEN1BRD4TAF1BRPF1 | |
| SCHEMBL40761 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108641092-A | The preparation method of supermolecule polymer composite micelle based on hydrogen bond | 辽宁大学 | 2018-10-12 | — | — | CN | disclosed |
| EP-1254219-A2 | NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES | Human Genome Sciences, Inc. (US) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055300-A2 | NUCLEIC ACIDS, PROTEINS, AND ANTIBODIES | HUMAN GENOME SCIENCES, INC. (US) | 2001-08-02 | — | — | WO | disclosed |