Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7137337 | 0.95 | NLRP3 (0.64) | NLRP3LPAR1 | |
| SCHEMBL7619278 | 0.90 | NLRP3 (0.54) | NLRP3LPAR1 | |
| SCHEMBL7617320 | 0.88 | NLRP3 (0.60) | NLRP3 | |
| SCHEMBL7145367 | 0.85 | NLRP3 (0.59) | NLRP3LPAR1 | |
| SCHEMBL7136055 | 0.83 | NLRP3 (0.65) | NLRP3 | |
| SCHEMBL7140501 | 0.83 | NLRP3 (0.75) | NLRP3 | |
| SCHEMBL7616971 | 0.81 | NLRP3 (0.66) | NLRP3 | |
| SCHEMBL7618626 | 0.81 | NLRP3 (0.52) | NLRP3 | |
| SCHEMBL7614942 | 0.79 | NLRP3 (0.69) | NLRP3 | |
| SCHEMBL7618689 | 0.78 | NLRP3 (0.48) | NLRP3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214087-A1 | COMBINATION TREATMENT WITH IL-1RA AND COMPOUNDS THAT INHIBIT IL-1 PROCESSING AND RELEASE | Pfizer Products Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019390-A1 | COMBINATION TREATMENT WITH IL-1RA AND DIARYL SULPHONYL UREA COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2001-03-22 | — | — | WO | disclosed |