SCHEMBL7614948

SCHEMBL7614948

N#CCC(=O)c1ccccc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
ALOX15 P16050 1/20 0.56
MAPT P10636 3/20 0.50
AKR1C3 P42330 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
MCL1 Q07820 1/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
KDM4E B2RXH2 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
HPGD P15428 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL395494 0.92 MAPT (0.56) ALDH1A1ALOX15MAPTKMT2AMEN1
SCHEMBL3687021 0.83 ALDH1A1 (0.47) ALDH1A1ALOX15MAPTKMT2AMEN1
SCHEMBL5685148 0.82 MAPT (0.49) ALDH1A1MAPTKMT2AMEN1MCL1
Phthalic Acid SCHEMBL27543485 0.80 ALDH1A1 (0.78) ALDH1A1ALOX15MAPTAKR1C3KDM4E
Phthalic Acid SCHEMBL27876734 0.80 ALDH1A1 (0.88) ALDH1A1ALOX15MAPTAKR1C3KDM4E
Phthalic Acid SCHEMBL27329792 0.80 ALDH1A1 (0.88) ALDH1A1ALOX15MAPTAKR1C3KDM4E
Phthalic Acid SCHEMBL10731126 0.80 ALDH1A1 (0.88) ALDH1A1ALOX15MAPTAKR1C3KDM4E
SCHEMBL11493775 0.80 MAPT (0.50) ALDH1A1MAPTKMT2AMEN1KDM4E
Phthalic Acid SCHEMBL27443690 0.80 ALDH1A1 (0.88) ALDH1A1ALOX15MAPTAKR1C3KDM4E
SCHEMBL4047052 0.79 BCAT2 (0.52) ALDH1A1MAPTKMT2AMEN1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112442284-B Isoindoline pigment and method for producing same 住友化学株式会社 2023-03-24 CN disclosed
CN-112521774-B Isoindoline pigment and method for producing same 住友化学株式会社 2022-07-08 CN disclosed
CN-108690372-B Isoindoline pigment and method for producing same 住友化学株式会社 2022-04-15 CN disclosed
CN-107024834-B Compound and coloring composition 住友化学株式会社 2021-11-23 CN disclosed
CN-107586469-B Pigment composition, coloring composition, and coloring curable composition 住友化学株式会社 2021-04-06 CN disclosed
CN-112521774-A Isoindoline pigment and method for producing same 住友化学株式会社 2021-03-19 CN disclosed
CN-112442284-A Isoindoline pigment and method for producing same 住友化学株式会社 2021-03-05 CN disclosed
CN-108690372-A Isoindoline pigment and method for producing same 住友化学株式会社 2018-10-23 CN disclosed
EP-1218360-A1 TRIAZINE KINASE INHIBITORS Amgen Inc., (US) 2002-07-03 EP disclosed
WO-2001025220-A1 TRIAZINE KINASE INHIBITORS AMGEN INC. (US) 2001-04-12 WO disclosed