Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HK1 | P19367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395494 | 0.90 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7614948 | 0.82 | ALDH1A1 (0.56) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9693886 | 0.81 | MAPT (0.49) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11493775 | 0.78 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| Water SCHEMBL7770314 | 0.78 | ALDH1A1 (0.67) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL28202480 | 0.78 | MAPT (0.47) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL741169 | 0.77 | KMT2A (0.54) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4941615 | 0.77 | MAPT (0.49) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL12605117 | 0.77 | MAPT (0.50) | MAPTKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL30605772 | 0.77 | MAPT (0.49) | MAPTKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638912-A2 | PROCESS FOR THE PREPARATION OF CINNAMALDEHYDE COMPOUNDS | Lymphosign Inc. (CA) | 2006-03-29 | — | — | EP | disclosed |
| US-20050033090-A1 | Process for the preparation of cinnamaldehyde compounds | LYMPHOSIGN INC. (CA) | 2005-02-10 | — | — | US | disclosed |
| WO-2005000777-A2 | PROCESS FOR THE PREPARATION OF CINNAMALDEHYDE COMPOUNDS | LYMPHOSIGN INC. (CA) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033090-A1 | Process for the preparation of cinnamaldehyde compounds | CES2, MCCC2, BCKDK | MAPT 3437/4885KDM4E 2342/4885ALDH1A1 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.