Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 1.00 |
| ▸ | MMP1 | P03956 | 8/20 | 1.00 |
| ▸ | MMP13 | P45452 | 8/20 | 1.00 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.71 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.51 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616849 | 1.00 | MMP9 (1.00) | MMP9MMP1MMP13KCNA5MMP2 | |
| SCHEMBL7615089 | 1.00 | MMP9 (1.00) | MMP9MMP1MMP13KCNA5MMP2 | |
| SCHEMBL7616843 | 1.00 | MMP9 (1.00) | MMP9MMP1MMP13KCNA5MMP2 | |
| SCHEMBL7379373 | 0.90 | MMP1 (0.81) | MMP9MMP1MMP13KCNA5BMP1 | |
| SCHEMBL7379371 | 0.90 | MMP1 (0.81) | MMP9MMP1MMP13KCNA5BMP1 | |
| SCHEMBL7355343 | 0.90 | MMP1 (0.81) | MMP9MMP1MMP13KCNA5BMP1 | |
| SCHEMBL7355335 | 0.90 | MMP1 (0.81) | MMP9MMP1MMP13KCNA5BMP1 | |
| SCHEMBL7355340 | 0.90 | MMP1 (0.81) | MMP9MMP1MMP13KCNA5BMP1 | |
| Hydroxyamine SCHEMBL7457010 | 0.88 | MMP1 (0.78) | MMP9MMP1MMP13KCNA5BMP1 | |
| Hydroxyamine SCHEMBL7457004 | 0.88 | MMP1 (0.78) | MMP9MMP1MMP13KCNA5BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934259-B1 | BETA-SULFONAMIDO HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID CO (US) | 2002-09-18 | — | — | EP | claimed |
| US-5977408-A | USEFUL FOR THE TREATMENT OF DISEASES IN WHICH THESE ENZYMES ARE IMPLICATED SUCH AS ARTHRITIS, TUMOR GROWTH AND METASTASIS, ANGIOGENESIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, PROTEINURIA | AMERICAN CYANAMID COMPANY (US) | 1999-11-02 | — | — | US | claimed |
| EP-0934259-B1 | BETA-SULFONAMIDO HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID CO (US) | 2002-09-18 | — | — | EP | disclosed |
| US-5977408-A | USEFUL FOR THE TREATMENT OF DISEASES IN WHICH THESE ENZYMES ARE IMPLICATED SUCH AS ARTHRITIS, TUMOR GROWTH AND METASTASIS, ANGIOGENESIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, PROTEINURIA | AMERICAN CYANAMID COMPANY (US) | 1999-11-02 | — | — | US | disclosed |