Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617024 | 0.92 | ALDH1A1 (0.38) | CNR2HPGDCNR1SMN1; SMN2HRH3 | |
| SCHEMBL7612492 | 0.90 | TP53 (0.39) | SMN1; SMN2 | |
| SCHEMBL7615681 | 0.89 | MAPK1 (0.43) | HPGDSMN1; SMN2 | |
| SCHEMBL7616570 | 0.88 | DRD2 (0.40) | CNR2SMN1; SMN2 | |
| SCHEMBL8476032 | 0.87 | CNR2 (0.52) | CNR2CNR1SMN1; SMN2 | |
| SCHEMBL9079757 | 0.86 | CNR2 (0.49) | CNR2HPGDCNR1SMN1; SMN2 | |
| SCHEMBL7612724 | 0.86 | ALDH1A1 (0.39) | HPGDSMN1; SMN2PTGER4 | |
| SCHEMBL8477117 | 0.85 | KDM4E (0.42) | HPGDSMN1; SMN2SLC6A4HRH3SLC6A2 | |
| SCHEMBL7613036 | 0.85 | KDM4E (0.38) | CNR2HPGDPTGER4 | |
| SCHEMBL8477343 | 0.84 | KDM4E (0.41) | HPGDSMN1; SMN2SLC6A4HRH3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |