Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.36 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615347 | 0.92 | CNR2 (0.44) | CNR2CNR1PTGER4HPGDSMN1; SMN2 | |
| SCHEMBL7612492 | 0.91 | TP53 (0.39) | ALDH1A1KMT2ATP53THRBSMN1; SMN2 | |
| SCHEMBL7615681 | 0.88 | MAPK1 (0.43) | ALDH1A1KMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL8479507 | 0.87 | CNR2 (0.44) | ALDH1A1L3MBTL1KMT2ACNR2HPGD | |
| SCHEMBL7616570 | 0.87 | DRD2 (0.40) | ALDH1A1CNR2SMN1; SMN2MAPK1HTT | |
| SCHEMBL7612724 | 0.86 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KMT2APTGER4TP53 | |
| SCHEMBL8476854 | 0.86 | PTGER4 (0.42) | ALDH1A1KMT2ACNR1PTGER4HPGD | |
| SCHEMBL8476916 | 0.84 | KDM4E (0.43) | ALDH1A1KMT2AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL7615408 | 0.84 | CNR2 (0.36) | ALDH1A1L3MBTL1KMT2ACNR2CNR1 | |
| SCHEMBL8479514 | 0.83 | PARP1 (0.38) | ALDH1A1KMT2ACNR2PTGER4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741132-B1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO KK (JP) | 2002-04-10 | — | — | EP | disclosed |
| EP-0741132-A1 | INDOLE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-11-06 | — | — | EP | disclosed |