SCHEMBL7615464

SCHEMBL7615464

Brc1ccccc1-c1ccc(Oc2ccc(-c3ccccc3Br)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
MAPK1 P28482 1/20 0.62
GSTP1 P09211 1/20 0.50
MCL1 Q07820 2/20 0.48
LTA4H P09960 5/20 0.42
TSHR P16473 2/20 0.42
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
ABL1 P00519 1/20 0.39
ABCB1 P08183 1/20 0.39
BCR P11274 1/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MAPT P10636 2/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12489603 0.85 ALDH1A1 (0.83) ALDH1A1MAPK1TSHRNPC1RAB9A
SCHEMBL30545203 0.83 ABL1 (0.60) ALDH1A1MAPK1LTA4HTSHRABL1
SCHEMBL7445927 0.83 ABL1 (0.60) ALDH1A1MAPK1LTA4HTSHRABL1
SCHEMBL30545205 0.83 ABL1 (0.60) ALDH1A1MAPK1LTA4HTSHRABL1
SCHEMBL673353 0.78 MAPK1 (0.71) ALDH1A1MAPK1TSHRNPC1RAB9A
SCHEMBL30121160 0.78 ALDH1A1 (0.90) ALDH1A1MAPK1TSHRNPC1RAB9A
SCHEMBL3778039 0.78 ALDH1A1 (0.90) ALDH1A1MAPK1TSHRNPC1RAB9A
SCHEMBL11751812 0.78 GSTP1 (0.61) ALDH1A1MAPK1GSTP1LTA4HTSHR
SCHEMBL4150746 0.78 ALDH1A1 (0.52) ALDH1A1MAPK1
SCHEMBL115115 0.78 ALDH1A1 (1.00) ALDH1A1MAPK1TSHRNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019118982-A1 MICROBE COMBINATIONS FOR BIOREMEDIATION AND METHODS OF USING THE SAME BIO-CAT MICROBIALS LLC (US) 2019-06-20 WO claimed
WO-2019118982-A1 MICROBE COMBINATIONS FOR BIOREMEDIATION AND METHODS OF USING THE SAME BIO-CAT MICROBIALS LLC (US) 2019-06-20 WO disclosed
EP-0812868-B1 Biodegradable elastomer and preparation process of same MITSUI CHEMICALS INC (JP) 2002-11-06 EP disclosed
US-6001891-A MADE BY CROSSLINKING A HIGH MOLECULAR WEIGHT ALIPHATIC POLYESTER CONTAINING AN ALIPHATIC SATURATED POLYBASIC ACID AND ALIPHATIC UNSATURATED POLYBASIC ACID; RUBBER-LIKE ELASTICITY, HARDNESS OF 80 OR LESS BY ASTM D676-58T MITSUI CHEMICALS, INC. (JP) 1999-12-14 US disclosed
EP-0812868-A1 Biodegradable elastomer and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-12-17 EP disclosed
US-5403477-A Sample preparation extractor comprising composite tube of polyolefin or fluoropolymer having on interior wall carbon allotrope particles to which contaminants adhere until removed by solvent; gas or liquid chromatography THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-04-04 US disclosed
US-5389251-A Organic contaminant separator THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-02-14 US disclosed
US-5308493-A Sampling and analyzing impurities in polymer composite tubes and passing solvents, analyzing with chromatography THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-05-03 US disclosed
US-5273655-A Passing a contaminated aqueous medium through a tube of a blend of polyolefin and polyester; dissolving the adhering impurities and chromatographically analyzing THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-12-28 US disclosed
EP-0149246-B1 OVERCOAT COMPOSITIONS CONTAINING NUCLEATING AGENTS AND ION-SELECTIVE ELECTRODES FOR CO2 DETERMINATIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-02-28 EP disclosed
EP-0149246-A2 Overcoat compositions containing nucleating agents and ion-selective electrodes for co2 determinations EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-07-24 EP disclosed
EP-0033707-B1 ELEMENT FOR LIQUID ANALYSIS HAVING INTERFERENT-REMOVAL ZONE AND METHOD FOR USING SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-06-20 EP disclosed
US-4303408-A EXTRACTION ZONE BEFORE INDICATOR ZONE EASTMAN KODAK COMPANY (US) 1981-12-01 US disclosed
EP-0033707-A1 Element for liquid analysis having interferent-removal zone and method for using same EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-08-12 EP disclosed