SCHEMBL7445927

SCHEMBL7445927

COc1ccc(-c2ccccc2Br)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.60
ABCB1 P08183 2/20 0.60
BCR P11274 2/20 0.60
ALDH1A1 P00352 1/20 0.58
MAPK1 P28482 1/20 0.58
HDAC4 P56524 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
PTPN1 P18031 1/20 0.51
BACE1 P56817 2/20 0.49
HTR1A P08908 1/20 0.46
HTR7 P34969 1/20 0.46
CA4 P22748 1/20 0.46
MAPT P10636 2/20 0.46
NPC1 O15118 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30545205 1.00 ABL1 (0.60) ABL1ABCB1BCRALDH1A1MAPK1
SCHEMBL30545203 1.00 ABL1 (0.60) ABL1ABCB1BCRALDH1A1MAPK1
SCHEMBL4447794 0.87 RXFP1 (0.60) ABL1ABCB1BCRALDH1A1MAPK1
SCHEMBL12715050 0.84 ABL1 (0.79) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL24860576 0.83 GSTP1 (0.59) ABL1ABCB1BCRALDH1A1MAPK1
SCHEMBL7615464 0.83 ALDH1A1 (0.62) ABL1ABCB1BCRALDH1A1MAPK1
SCHEMBL11096260 0.82 ABL1 (0.76) ABL1ABCB1BCRHDAC4HDAC2
SCHEMBL364849 0.82 ABL1 (0.63) ABL1ABCB1BCRALDH1A1MAPK1
SCHEMBL12489603 0.82 ALDH1A1 (0.83) ALDH1A1MAPK1MAPTNPC1TP53
SCHEMBL11819228 0.80 ABL1 (0.73) ABL1ABCB1BCRALDH1A1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043371-A1 NOVEL SPIROFLUORENE COMPOUND AND ORGANIC LIGHTEMITTING DEVICE INCLUDING SAME EMTIER CO., LTD. (KR) 2024-02-08 US disclosed
CN-116670112-A Novel spirofluorene compound and organic light-emitting device comprising same 韩国深通新材料株式会社 2023-08-29 CN disclosed
US-20230150919-A1 Method for Producing Mono-Cross-Coupled Aromatic Compound Having Leaving Group NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-05-18 US disclosed
US-20230150919-A1 Method for Producing Mono-Cross-Coupled Aromatic Compound Having Leaving Group NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-05-18 US disclosed
EP-4116282-A1 METHOD FOR PRODUCING MONO-CROSS-COUPLED AROMATIC COMPOUND HAVING LEAVING GROUP National University Corporation Hokkaido University (JP) 2023-01-11 EP disclosed
WO-2022131669-A1 NOVEL SPIROFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME 주식회사 센텀머티리얼즈 2022-06-23 WO disclosed
WO-2022131669-A1 NOVEL SPIROFLUORENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME 주식회사 센텀머티리얼즈 2022-06-23 WO disclosed
EP-3577101-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-03-03 EP disclosed
WO-2020041369-A1 METHODS FOR THE SYNTHESIS OF HETEROATOM CONTAINING POLYCYCLIC AROMATIC HYDROCARBONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-02-27 WO disclosed
CN-109456301-A A kind of HBC compound and its preparation and application containing crown ether 东华大学 2019-03-12 CN disclosed
CN-105646480-B Phenanthroline compound and application thereof 机光科技股份有限公司 2018-11-16 CN disclosed
WO-2018141706-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-08-09 WO disclosed
CN-105646480-A Phenanthroline compound and application thereof 机光科技股份有限公司 2016-06-08 CN disclosed
CN-102286213-A Near-infrared aza-BODIPY dye as well as preparation method and application thereof 2011-12-21 CN disclosed
US-6265575-B1 THROMBIN INHIBITORS ELI LILLY AND COMPANY 2001-07-24 US disclosed
EP-0863755-A4 ANTITHROMBOTIC DIAMINES LILLY CO ELI (US) 1999-01-20 EP disclosed
EP-0863755-A1 ANTITHROMBOTIC DIAMINES ELI LILLY AND COMPANY (US) 1998-09-16 EP disclosed
WO-1997025033-A1 ANTITHROMBOTIC DIAMINES ELI LILLY AND COMPANY (US) 1997-07-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150919-A1 Method for Producing Mono-Cross-Coupled Aromatic Compound Having Leaving Group DDC, PAH, ATIC ABL1 331/4885ABCB1 1329/4885BCR 187/4885
US-20240043371-A1 NOVEL SPIROFLUORENE COMPOUND AND ORGANIC LIGHTEMITTING DEVICE INCLUDING SAME INMT, TRPA1, ICMT ABL1 1065/4885ABCB1 2724/4885BCR 1407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.